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Creatine for Muscle Strength and Growth

When it comes to muscle development and growth, creatine is considered a cornerstone supplement.

Key Takeaways:

  • Creatine is effective for improving performance, strength, and muscle growth processes.
  • Creatine enhances muscle strength and growth primarily by increasing ATP levels (main energy molecule), allowing for improved performance and greater training capacity.
  • Additionally, creatine increases muscle cell hydration, giving muscles a fuller look and creating an environment favorable for muscle growth and recovery.

 

 

Human Studies 🔬

 

💪 Muscle Strength

  • "...Creatine supplementation facilitates more significant improvements in strength and fat-free mass...provides positive benefits to both males and females, athletes and recreational fitness enthusiasts, as well as younger and older individuals" [1]
  • "After supplementation, the maximal strength in the creatine group significantly increased..." [2]
  • "There is substantial evidence to indicate that a low-dose, short-term oral Creatine supplementation beneficially affected muscle power output in elite youth soccer players." [3]
  • "These results support a number of earlier studies that demonstrated that creatine supplementation at low doses and without the use of the loading phase are effective for increasing maximal strength and endurance of upper limbs." [4]

 

💪 Muscle Growth

  • A 2022 review of 16 randomized controlled trials has concluded: "Overall, creatine is an efficient form of supplementation for muscle growth in the healthy young population with adequate training in a variety of dosage strategies and athletic activities." [5]
  • Another 2 systematic reviews and meta-analysis have also concluded creatine's efficiency in improving muscle growth, both in younger and older adults. [6, 7]
A forest plot displaying the results of a meta-analysis on the efficacy of creatine supplementation combined with resistance training for muscle hypertrophy. Each study is represented by a horizontal line indicating the controlled standardized mean difference effect size, with confidence intervals shown as shaded areas. The studies include findings from Candow et al. (2011) to Raschke et al. (2021), with effect sizes ranging from -0.21 to 0.47. The average effect size is marked at the bottom as 0.22 (95% CI: 0.10, 0.34), indicating a statistically significant positive effect on muscle hypertrophy. A green scale illustrates the magnitude of the effect.

Meta-analysis of the Efficacy of Creatine supplementation combined with resistance training on Muscle Hypertrophy (adapted from Burke, R. et al., 2023)

 

 

🔝 Height

  • What's also interesting, a study of 4291 participants, aged 2 to 19 years, who provided valid dietary information and examination measure, have shown that: "Each additional 0.1 g of creatine consumed per day increases height by 0.60 cm (simple model) or 0.30 cm (adjusted model). The daily intake of creatine from a regular diet in taller children and adolescents was higher than in shorter peers aged 2–19 years." [8]

 

 

Conclusion

Creatine has firmly established its place as one of the most effective supplements for enhancing muscle strength and growth.

From improving ATP availability to fostering better muscle recovery, its benefits are backed by decades of research.

Whether you’re young, old, an elite athlete, or a recreational gym-goer, creatine offers something for everyone aiming to unlock their full strength potential.

With proper use and consistent training, creatine can help you break through plateaus and achieve the performance and physique you’ve always desired.

So, are you ready to take your fitness journey to the next level?

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FAQ

What is creatine?

Creatine is a natural substance found in the body’s cells.

It helps produce energy in high-demand tissues like the muscles and brain.

What does creatine do?

Creatine boosts energy, improves muscle strength and endurance, accelerates recovery, and also supports cognitive function and brain health.

It helps you perform better and recover faster.

How does creatine work?

Creatine increases phosphocreatine stores in your muscles, allowing for faster energy production during intense exercise. This leads to improved performance, strength, and recovery. Phosphocreatine is a high-energy compound stored in muscles that helps regenerate ATP (adenosine triphosphate), the primary energy currency of cells, during short bursts of effort.

Creatine also supports brain health by enhancing energy availability in brain cells, which may improve cognitive performance, mental clarity, and resistance to mental fatigue — especially under stress or during sleep deprivation.

What is creatine good for?

Creatine is good for increasing muscle strength, enhancing athletic performance, improving recovery times, and even supporting brain health.

How much creatine should I take per day?

A common recommendation is around 5 grams per day.

If you want to dose like a pro, a creatine-loading phase (20 g/day for up to 7 days), followed by a creatine maintenance phase (3–5 g/day), is typically sufficient to produce skeletal muscle benefits. [R]

Alternatively, a relative dosing strategy of 0.10–0.14 g of creatine per kg of body weight per day may also be a viable option, especially for healthy older adults. [R]

For brain health, a common dosage is around 10 g per day (2-20 g in studies). [21] However, after sleep deprivation, increasing the dosage to 0.35 g/kg may enhance cognitive performance and mental clarity. [22]

As always, it’s best to consult a healthcare professional.

When to take creatine?

You can take creatine at any time. Studies have shown that there is no optimal time for taking creatine. [R]

It is better to take it with some amount of carbohydrates (around 15-20 g), for greater uptake of creatine, compared to creatine alone. [R]

How to take creatine?

Mix the recommended dose with water or your favorite beverage. It can also be added to smoothies or protein shakes for convenience.

It is better to take it with some amount of carbohydrates (around 15-20 g), for greater uptake of creatine, compared to creatine alone. [R]

What does creatine do for 👨men?

For men, creatine enhances muscle strength and endurance, increases workout intensity, and supports faster recovery, making it ideal for resistance training and high-intensity sports.

It also supports cognitive performance, brain and mental health. [R]

What does creatine do for 👩women?

Creatine offers women similar to men benefits: improved muscle strength, better endurance, and quicker recovery. It's effective for enhancing performance in various fitness activities.

It also can support cognitive performance, if taken in higher dosages (0.35 g/kg of body weight) and during fatigue state. [R]

How long does creatine take to work?

Many users start noticing benefits within a week of consistent use, but full effects can take several weeks.

For cognitive performance after sleep deprivation, it is effective after a single use, but in higher dosage (0.35 g/kg of body weight). [R]

How much creatine per day to 💪build muscle?

A common recommendation is around 5 grams per day.

If you want to dose like a pro, a creatine-loading phase (20 g/day for ≤ 7 days), and a creatine maintenance phase (3–5 g/day) appears sufficient to produce skeletal muscle benefits. [R]

Alternatively, a relative dosing strategy of 0.10–0.14 g of creatine/kg/day appears to be a viable option, especially for healthy older adults. [R]

It's best to consult a healthcare professional.

All statements on this page have not been evaluated by regulatory agencies in all jurisdictions. The products mentioned here are not intended to diagnose, treat, cure, or prevent any disease. This is not medical advice.

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